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ALK inhibitor SB 525334, Purity ≥98%
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Cat. No.: X23-10-ZQ806

ALK inhibitor SB 525334, Purity ≥98%

Synonym: 356559-20-1; SB-525334; SB 525334; SB525334; 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline; 6-[2-tert-BUTYL-5-(6-METHYL-PYRIDIN-2-YL)-1H-IMIDAZOL-4-YL]-QUINOXALINE; ALK inhibitor

  • MDL: MFCD11045307
  • CAS Number: 356559-20-1
  • Compound CID: 9967941
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
SB 525334, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against ALK. It targets TGFβR1 (ALK5).
Molecular Weight
343.4
Molecular Formula
C21H21N5
Targets
TGFβR1 (ALK5): 14.3 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 67 mg/mL (195.09 mM); Water: Insoluble; Ethanol: 67 mg/mL (195.09 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SB 525334 can be used to investigate its selective inhibition of TGF-β receptor type I and its potential therapeutic applications.
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