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ALK inhibitor, TAE684, Purity ≥98%
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Cat. No.: X24-09-YM696

ALK inhibitor, TAE684, Purity ≥98%

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Synonym: 761439-42-3; NVP-TAE684; TAE-684; 5-Chloro-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine; ALK inhibitor

  • MDL: MFCD11977634
  • CAS Number: 761439-42-3
  • Compound CID: 16038120
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TAE684, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of LRRK1 by inhibiting Protein Tyrosine Kinases. The molecular weight of the compound is 614.2, and its molecular formula is C30H40ClN7O3S. It targets the ALK (Cell-free assay).
Molecular Weight
614.2
Molecular Formula
C30H40ClN7O3S
Targets
ALK (Cell-free assay)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 3 mg/mL (4.88 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% PEG400 + 0.5% Tween80 + 5% propylene glycol, pH 4, 9 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAE684 can be used for its effects in ALK-positive cancers, such as non-small cell lung cancer (NSCLC).
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