Alniditan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1B receptor, 5-HT1D receptor, human 5-HT1B receptor, and human 5-HT1D receptor.
Molecular Weight
302.41
Molecular Formula
C17H26N4O
Targets
5-HT1B receptor: 0.9 nM (Kd); 5-HT1D receptor: 1.2 nM (Kd); Human 5-HT1B receptor: 1.7 nM (IC50, in HEK 293 cell); Human 5-HT1D receptor: 1.3 nM (IC50, in HEK 293 cell)
Form
Lyophilized powder
Purity
>98%
Applications
Alniditan can be studied for its effect on reducing the frequency and severity of migraine attacks.
Publications
Publications (0)
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Publications
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