AMG-073 HCl (cinacalcet HCl), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets CaSR.
AMG-073 HCl (cinacalcet HCl) can be used for its effect on binding to and activating calcium-sensing receptors on the parathyroid gland.
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