Properties
                                        
                            Description
                            AMG-073 HCl (cinacalcet HCl), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets CaSR.
                         
                                                                            
                                                            
                            Molecular Formula
                            C22H23ClF3N
                         
                                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                            
                                                                                                                                                                            
                            Solubility
                            DMSO: 67 mg/mL (170.1 mM); Water: insoluble; Ethanol: 28 mg/mL (71.09 mM)
                         
                                                                                                                                                                            
                            Applications
                            AMG-073 HCl (cinacalcet HCl) can be used for its effect on binding to and activating calcium-sensing receptors on the parathyroid gland.