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Aminopterin APGA targeting molecule-modified artemether liposomes

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Cat. No.: X26-05-ZQ2890

Aminopterin APGA targeting molecule-modified artemether liposomes

Name: Aminopterin APGA targeting molecule-modified artemether liposomes
SKU: X26-05-ZQ2890

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Synonym: Aminopterin APGA-modified artemether LPs; Aminopterin APGA targeted artemether liposomes; Aminopterin APGA-functionalized artemether liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced multi-functional targeted formulation features APGA targeting molecule-modified and artemether loaded liposomes. The structural framework incorporates the hydrophobic sesquiterpene lactone compound artemether directly within the lipophilic hydrocarbon tail domains of its bilayer shell, whose exterior boundary is surface-modified with specific aminopterin-derived aminopterin-pteroylglutamic acid (APGA) targeting ligands linked via covalent polymer-lipid anchors. This complex configuration coordinates a dense target-mimetic ligand array with an optimized sesquiterpene matrix, altering overall surface hydration parameters to completely prevent physical vesicle aggregation while shielding the volatile peroxide bridges of artemether from rapid chemical degradation in open laboratory media.

Source

Custom synthesis

Functional Group

Aminopterin pteroylglutamic acid (APGA); Artemether

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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