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Antisense oligonucleotide/span-modified cationic liposomes

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Cat. No.: X26-05-ZQ2017

Antisense oligonucleotide/span-modified cationic liposomes

Name: Antisense oligonucleotide/span-modified cationic liposomes
SKU: X26-05-ZQ2017

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Synonym: ASODN/span-modified cationic liposomes; Antisense oligonucleotide span-modified cationic LPs; ASODN-span cationic lipoplexes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This complex formulation features antisense oligonucleotide/span-modified cationic liposomes designed as a surfactant-hybrid oligonucleotide condensation matrix. The structural matrix incorporates lipophilic sorbitan fatty acid esters (such as Span surfactants) into a cationic lipid vesicle base to modulate membrane fluidity and packing defects, while the positive surface potential electrostatically condenses single-stranded antisense oligonucleotide sequences into a stable lipoplex matrix. This detailed configuration coordinates the non-ionic sorbitan surfactants and cationic headgroups to optimize oligonucleotide stability, preventing physical vesicle aggregation and nucleic acid precipitation under ambient laboratory conditions.

Source

Custom synthesis

Functional Group

Antisense oligonucleotide; Span; Cationic lipid

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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