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Aptamer DNA-modified liposome-encapsulated ZIF-8 loaded with RNA

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Cat. No.: X26-05-ZQ2834

Aptamer DNA-modified liposome-encapsulated ZIF-8 loaded with RNA

Name: Aptamer DNA-modified liposome-encapsulated ZIF-8 loaded with RNA
SKU: X26-05-ZQ2834

Inquiry

Synonym: Aptamer DNA-modified liposome@ZIF-8@RNA; Aptamer DNA liposome-encapsulated ZIF-8@RNA; Aptamer DNA-functionalized liposome@ZIF-8 loaded with RNA

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced complex multi-shell hybrid material features an oligonucleotide aptamer functionalized liposome template enveloping a metal-organic framework core loaded with nucleic acids. The complex architecture incorporates a ribonucleic acid (RNA) molecule core-encapsulated inside an interior crystalline shell of the zeolitic imidazolate framework-8 (ZIF-8) metal-organic framework, completely enclosed within an exterior phospholipid vesicle template whose outermost boundary is surface-functionalized with specific single-stranded oligonucleotide DNA aptamers linked via lipid anchors. This intricate configuration coordinates intense targeted oligonucleotide arrays with the rigid porous mass transfer resistance of a metal-organic framework shield and the flexible fluid dynamics of a lipid envelope, completely protecting the fragile internal nucleic acids from ribonuclease-mediated water degradation while preventing physical particle aggregation under ambient laboratory testing conditions.

Source

Custom synthesis

Functional Group

DNA Aptamer; ZIF-8 MOF core; RNA cargo

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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