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ATM inhibitor-1, Purity ≥98%
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Cat. No.: X24-05-ZQ304

ATM inhibitor-1, Purity ≥98%

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Synonym: 2135639-94-8; ATM Inhibitor-1; CHEMBL4218854; 6-[6-[3-(Dimethylamino)propoxy]pyridin-3-yl]-N-methyl-4-[[(1S)-1-(oxan-4-yl)ethyl]amino]cinnoline-3-carboxamide; SCHEMBL19384258; ATM-ATR inhibitor

  • CAS Number: 2135639-94-8
  • Compound CID: 130453737
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Product Size
1 mg; 5 mg; 10 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ATM inhibitor-1 interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATM, ATM, DNAPK, mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
492.61
Molecular Formula
C27H36N6O3
Targets
ATM: 0.7 nM; ATM: 2.8 nM (IC50, cellular assay); DNAPK: 2.8 μM; mTOR: 21 μM; PI3Kα: 3.8 μM; PI3Kβ: 10.3 μM; PI3Kδ: 0.73 μM; PI3Kγ: 3 μM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
ATM inhibitor-1 is utilized to study the inhibition of ataxia-telangiectasia mutated (ATM) in DNA damage response research.
Publications
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