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Aurora kinase inhibitor ENMD-2076 tartrate, Purity ≥98%

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Cat. No.: X24-05-ZQ844

Aurora kinase inhibitor ENMD-2076 tartrate, Purity ≥98%

Synonym: 1291074-87-7; ENMD2076; ENMD 2076; Aurora kinase inhibitor

CAS Number: 1291074-87-7
Compound CID: 66576993

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

ENMD-2076 tartrate, soluble in warmed DMSO and insoluble in water and ethanol, inhibits Aurora kinases, which play crucial roles in cell division by controlling chromosome segregation and cytokinesis. It targets Aurora A, FGFR1, FGFR2, and Flt-4.

Molecular Weight

525.56

Molecular Formula

C₂₅H₃₁N₇O₆

Targets

Aurora A: 1.86 nM; FGFR1: 92.7 nM; FGFR2: 70.8 nM; Flt-4: 15.9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 86 mg/mL (163.63 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

ENMD-2076 tartrate is used to explore its effects as a multi-kinase inhibitor, particularly targeting Aurora A and angiogenesis-related kinases.

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