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Aurora kinase inhibitor Reversine, Purity ≥98%

Cat. No.: X24-05-ZQ843

Aurora kinase inhibitor Reversine, Purity ≥98%

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Synonym: 656820-32-5; Reversine; 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; CHEMBL188343; CHEBI:70723; Aurora kinase inhibitor

  • CAS Number: 656820-32-5
  • Compound CID: 210332
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Reversine, soluble in warmed DMSO and insoluble in water and ethanol, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, Aurora C, and human A3 adenosine receptor.
Molecular Weight
393.5
Molecular Formula
C21H27N7O
Targets
Aurora A: 12 nM; Aurora B: 13 nM; Aurora C: 20 nM; Human A3 adenosine receptor: 0.66 μM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 4 mg/mL (10.17 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Reversine is used to study its role as a multi-kinase inhibitor affecting cell differentiation and proliferation.
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