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Autophagy inhibitor, SMER28, Purity ≥98%

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Cat. No.: X24-09-YM670

Autophagy inhibitor, SMER28, Purity ≥98%

Synonym: 307538-42-7; SMER 28; SMER-28; 6-Bromo-N-prop-2-enylquinazolin-4-amine; Autophagy inhibitor

MDL: MFCD02166825
CAS Number: 307538-42-7
Compound CID: 1560402

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

SMER28, soluble in DMSO and ethanol and insoluble in water, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 264.12, and its molecular formula is C₁₁H₁₀BrN₃.

Molecular Weight

264.12

Molecular Formula

C₁₁H₁₀BrN₃

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 49 mg/mL (185.52 mM); Water: insoluble; Ethanol: 49 mg/mL (185.52 mM); In vivo: 2% DMSO + 30% PEG 300 + ddH₂O, 14 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

SMER28 plays a key role in activating the mTOR pathway in a manner that promotes cellular degradation of damaged proteins and organelles.

Publications

Publications (0)

Publications

Publications

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