Properties
Description
Azithromycin-chondroitin sulfate antimicrobial conjugate links the macrolide antibiotic via pH-labile bonds to chondroitin's hydroxyl groups, enabling site-specific drug release.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→21 linked)
Source
Chemical synthesis
Functional Group
Azithromycin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-azithromycin can be used for its potential to develop macrolide antibiotic carriers for intracellular bacterial infections.