Bindarit, soluble in DMSO and ethanol and insoluble in water, is an anti-inflammatory small molecule that modulates the NFκB pathway. The molecular weight of the compound is 324.37, and its molecular formula is C19H20N2O3.
Molecular Weight
324.37
Molecular Formula
C19H20N2O3
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 61 mg/mL (188.05 mM); Water: insoluble; Ethanol: 61 mg/mL (188.05 mM); In vivo: 0.5% CMC, 6 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Bindarit can be studied extensively for its potential therapeutic applications in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis, by reducing the recruitment of inflammatory cells to sites of injury.
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