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BMY 7378

Inquiry

Cat. No.: X23-12-YM512

BMY 7378

Synonym: 21102-95-4; 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride

CAS Number: 21102-95-4
Compound CID: 210172

Product Size

10 mg; 50 mg; 200 mg; 500 mg

Price

Datasheet

MSDS

Properties

Description

BMY 7378, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1D-adrenoceptor, DopamineD2 receptor, α2-adrenoceptor, α2C-adrenoceptor, β1-adrenoceptor, β2-adrenoceptor, 5-HT1A, 5-HT1C, 5-HT1D, 5-HT2, and 5-HT3.

Molecular Weight

458.42

Molecular Formula

C₂₂H₃₁N₃O₃·2HCl

Targets

α1D-adrenoceptor: 8.2 (pki); Dopamine D2 receptor: 7.4 (pIC₅₀); α2-Adrenoceptor: 5.1 (pIC₅₀); α2C-adrenoceptor: 6.54 (pki); β1-Adrenoceptor: 5.1 (pIC₅₀); β2-Adrenoceptor: <5.0 (pIC₅₀); 5-HT1A: 8.3 (pIC₅₀); 5-HT1C: 6.4 (pIC₅₀); 5-HT1D: 5.9 (pIC₅₀); 5-HT2: 5.5 (pIC₅₀); 5-HT3: <5.0 (pIC₅₀)

Form

Lyophilized powder

Purity

Solubility

DMSO: 81 mg/mL (176.69 mM); Water: 81 mg/mL (176.69 mM); Ethanol: 18 mg/mL (39.26 mM)

Applications

BMY 7378 can be used to modulate serotonin signaling pathways, potentially influencing conditions associated with serotonin dysfunction.

Publications

Publications (0)

Publications

Publications

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