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BMY 7378
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Cat. No.: X23-12-YM512

BMY 7378

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Synonym: 21102-95-4; 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride

  • CAS Number: 21102-95-4
  • Compound CID: 210172
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Product Size
10 mg; 50 mg; 200 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BMY 7378, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1D-adrenoceptor, DopamineD2 receptor, α2-adrenoceptor, α2C-adrenoceptor, β1-adrenoceptor, β2-adrenoceptor, 5-HT1A, 5-HT1C, 5-HT1D, 5-HT2, and 5-HT3.
Molecular Weight
458.42
Molecular Formula
C22H31N3O3·2HCl
Targets
α1D-adrenoceptor: 8.2 (pki); Dopamine D2 receptor: 7.4 (pIC50); α2-Adrenoceptor: 5.1 (pIC50); α2C-adrenoceptor: 6.54 (pki); β1-Adrenoceptor: 5.1 (pIC50); β2-Adrenoceptor: <5.0 (pIC50); 5-HT1A: 8.3 (pIC50); 5-HT1C: 6.4 (pIC50); 5-HT1D: 5.9 (pIC50); 5-HT2: 5.5 (pIC50); 5-HT3: <5.0 (pIC50)
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 81 mg/mL (176.69 mM); Water: 81 mg/mL (176.69 mM); Ethanol: 18 mg/mL (39.26 mM)
Applications
BMY 7378 can be used to modulate serotonin signaling pathways, potentially influencing conditions associated with serotonin dysfunction.
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