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Brequinar-loaded mitochondrion-targeted liposomes (BQR@M LPs)
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Cat. No.: X26-05-ZQ1475

Brequinar-loaded mitochondrion-targeted liposomes (BQR@M LPs)

Synonym: Brequinar mitochondrion-targeted liposomes; BQR-loaded mitochondrion-targeted LPs; BQR@M liposomes; BQR@M LPs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly engineered delivery system features brequinar-loaded mitochondrion-targeted liposomes (BQR@M LPs). The vesicle architecture utilizes a stable phospholipid bilayer that encapsulates the hydrophobic dihydroorotate dehydrogenase inhibitor brequinar (BQR) within its hydrocarbon core, while the outer surface is functionalized with specific mitochondrion-targeting ligands (such as triphenylphosphonium derivatives) covalently linked to lipid anchors. This structural configuration introduces a distinctive positive surface charge topography and alters overall membrane elasticity. The resulting nanoparticles exhibit high colloidal stability and a highly uniform spherical morphology for advanced transport modeling.
Source
Custom synthesis
Functional Group
Brequinar
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)

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