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BRL-54443

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Cat. No.: X23-12-YM963

BRL-54443

Synonym: 57477-39-1; 3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol

CAS Number: 57477-39-1
Compound CID: 2438

Product Size

10 mg; 25 mg; 100 mg; 200 mg

Price

Datasheet

MSDS

Properties

Description

BRL-54443, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT6 receptor, and 5-HT7 receptor.

Molecular Weight

230.31

Molecular Formula

C₁₄H₁₈N₂O

Targets

5-HT1A receptor: 63 nM; 5-HT1B receptor: 126 nM; 5-HT1D receptor: 63 nM; 5-HT1E receptor: 1.1 nM; 5-HT1F receptor: 0.7 nM; 5-HT2A receptor: 1259 nM; 5-HT2B receptor: 100 nM; 5-HT2C receptor: 316 nM; 5-HT6 receptor: >10,000 nM; 5-HT7 receptor: >10,000 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 40 mg/mL (173.68 mM); Water: insoluble; Ethanol: 2 mg/mL (8.68 mM)

Applications

BRL-54443 can be used for its ability to modulate the endocannabinoid system to influence these processes.

Publications

Publications (0)

Publications

Publications

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