PLX647 blocks the activity of the colony-stimulating factor-1 receptor (CSF1R), also known as c-FMS, which is implicated in various pathological conditions including certain cancers and inflammatory diseases by modulating macrophage recruitment and function.
Molecular Weight
382.38
Molecular Formula
C21H17F3N4
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
PLX647 is used in scientific studies focusing on the inhibition of c-FMS, aiding in the exploration of its role in cancer and inflammatory diseases by blocking macrophage recruitment and activation.
Publications
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Publications
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