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c-MET inhibitor EMD-1214063, Purity ≥98%
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Cat. No.: X24-06-ZQ207

c-MET inhibitor EMD-1214063, Purity ≥98%

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Synonym: 1100598-32-0; c-MET inhibitor; EMD1214063

  • CAS Number: 1100598-32-0
  • Compound CID: 25171648
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
EMD-1214063, soluble in warmed DMSO and insoluble in water and ethanol, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets IRAK4, TrkA, Axl, c-Met, IRAK1, Mer, RON, and TrkB.
Molecular Weight
492.6
Molecular Formula
C29H28N6O2
Targets
IRAK4: 615 nM; TrkA: 1.017 μM; Axl: 1.566 μM; c-Met: 4 nM; IRAK1: 2.037 μM; Mer: 2.272 μM; RON: >10 μM; TrkB: 5.716 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 4 mg/mL (8.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EMD-1214063 targets c-MET, advancing research on therapeutic strategies aimed at inhibiting this receptor in cancer.
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