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c-MET inhibitor EMD-1214063, Purity ≥98%

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Cat. No.: X24-06-ZQ207

c-MET inhibitor EMD-1214063, Purity ≥98%

Synonym: 1100598-32-0; c-MET inhibitor; EMD1214063

CAS Number: 1100598-32-0
Compound CID: 25171648

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

EMD-1214063, soluble in warmed DMSO and insoluble in water and ethanol, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets IRAK4, TrkA, Axl, c-Met, IRAK1, Mer, RON, and TrkB.

Molecular Weight

492.6

Molecular Formula

C₂₉H₂₈N₆O₂

Targets

IRAK4: 615 nM; TrkA: 1.017 μM; Axl: 1.566 μM; c-Met: 4 nM; IRAK1: 2.037 μM; Mer: 2.272 μM; RON: >10 μM; TrkB: 5.716 μM

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 4 mg/mL (8.12 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

EMD-1214063 targets c-MET, advancing research on therapeutic strategies aimed at inhibiting this receptor in cancer.

Publications

Publications (0)

Publications

Publications

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