c-MET inhibitor PF-2341066, Purity ≥98%

Synonym: 877399-52-5; c-MET inhibitor; PF02341066

MDL: MFCD12407409
CAS Number: 877399-52-5
Compound CID: 11626560

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PF-2341066 inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets ALK (Karpas299 cells) and c-Met (A549, MDA-MB-231, GTL-16, HT29, 786-O, Colo-205, A498 cells).

Molecular Weight

450.3

Molecular Formula

C₂₁H₂₂Cl₂FN₅O

Targets

ALK (Karpas 299 cells): 24 nM; c-Met: 11 nM

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-2341066 is a c-MET inhibitor, applied in studying its role in cancer metastasis and treatment resistance.