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c-MET inhibitor PF-2341066, Purity ≥98%
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Cat. No.: X24-06-ZQ221

c-MET inhibitor PF-2341066, Purity ≥98%

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Synonym: 877399-52-5; c-MET inhibitor; PF02341066

  • MDL: MFCD12407409
  • CAS Number: 877399-52-5
  • Compound CID: 11626560
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PF-2341066 inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets ALK (Karpas299 cells) and c-Met (A549, MDA-MB-231, GTL-16, HT29, 786-O, Colo-205, A498 cells).
Molecular Weight
450.3
Molecular Formula
C21H22Cl2FN5O
Targets
ALK (Karpas 299 cells): 24 nM; c-Met: 11 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-2341066 is a c-MET inhibitor, applied in studying its role in cancer metastasis and treatment resistance.
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