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c-MET inhibitor SGX-523, Purity ≥98%
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Cat. No.: X24-06-ZQ223

c-MET inhibitor SGX-523, Purity ≥98%

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Synonym: 1022150-57-7; c-MET inhibitor; SGX523

  • CAS Number: 1022150-57-7
  • Compound CID: 24779724
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SGX-523, soluble in warmed DMSO and insoluble in water and ethanol, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets B-Raf (V599E), C-Raf, Abl, Abl1 (Y253F), c-Met, and p38α.
Molecular Weight
359.4
Molecular Formula
C18H13N7S
Targets
B-Raf (V599E): >7 μM; C-Raf: >7 μM; Abl: >7 μM; Abl1 (Y253F): >7 μM; c-Met: 4 nM; p38α: >7 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 3 mg/mL (8.34 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SGX-523 investigates c-MET inhibition, relevant in studies of novel cancer treatment strategies targeting MET-dependent tumors.
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