Properties
Description
ACT-709478 blocks the entry of calcium into cells, particularly in the heart and blood vessels. It targets Cav1.2, CaV3.1, Cav3.2, and CaV3.3.
Molecular Formula
C22H18F3N5O
Targets
Cav1.2: 2410 nM; CaV3.1: 6.4 nM; Cav3.2: 18 nM; CaV3.3: 7.5 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
ACT-709478 helps in investigating its role in inhibiting cellular calcium influx, crucial for muscle function.