Properties
Description
Bay K 8644, soluble in DMSO and ethanol and insoluble in water, blocks the entry of calcium into cells, particularly in the heart and blood vessels. It targets L-type calcium channel.
Molecular Formula
C16H15F3N2O4
Targets
L-type calcium channel: 17.3 nM (EC50)
Solubility
DMSO: 66 mg/mL (185.24 mM); Water: Insoluble; Ethanol: 66 mg/mL (185.24 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Bay K 8644 is a calcium channel inhibitor employed in research to study calcium’s role in muscle contraction and neurotransmitter release.