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Caspase inhibitor Belnacasan, Purity ≥98%

Cat. No.: X23-10-ZQ056

Caspase inhibitor Belnacasan, Purity ≥98%

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Synonym: 273404-37-8; BELNACASAN; VX-765; Belnacasan (VX-765); VX765; Belnacasan [USAN]; (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; Caspase inhibitor

  • MDL: MFCD11100350
  • CAS Number: 273404-37-8
  • Compound CID: 11398092
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Belnacasan, soluble in warmed DMSO and warmed ethanol and insoluble in water, inhibits the activity of caspases, thereby preventing apoptosis. It targets Caspase-4 and Caspase-1.
Molecular Weight
509
Molecular Formula
C24H33ClN4O6
Targets
Caspase-4: <0.6 nM (Ki); Caspase-1: 0.8 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 87 mg/mL (170.92 mM); Water: Insoluble; Warmed ethanol: 87 mg/mL (170.92 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Belnacasan (VX-765) can be used to research the inhibition of interleukin-1尾 converting enzyme (caspase-1) and its effects on inflammatory diseases.
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