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Caspase inhibitor Z-VAD-FMK, Purity ≥98%
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Cat. No.: X23-10-ZQ061

Caspase inhibitor Z-VAD-FMK, Purity ≥98%

Synonym: 187389-52-2; Z-VAD(OMe)-FMK; Z-Val-Ala-Asp(OMe)-FMK; Pan-caspase inhibitor; 5-Bromo-2 -deoxyuridine; Methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate; Caspase inhibitor

  • MDL: MFCD02684037
  • CAS Number: 187389-52-2
  • Compound CID: 5497174
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Product Size
1 mg; 5 mg; 10 mg; 25 mg
Price
Datasheet
MSDS
Properties
Description
Z-VAD-FMK, soluble in DMSO and insoluble in ethanol and water, inhibits the activity of caspases, thereby preventing apoptosis. It targets pan-caspase (THP.1, Jurkat T-cells).
Molecular Weight
467.49
Molecular Formula
C22H30FN3O7
Targets
Pan-caspase (THP.1, Jurkat T-cells): 0.0015-5.8 mM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 80 mg/mL (171.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Z-VAD-FMK can be used to broadly inhibit caspases in research focused on apoptosis and necroptosis pathways.
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