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CCR inhibitor Cenicriviroc, Purity ≥98%
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Cat. No.: X23-10-ZQ589

CCR inhibitor Cenicriviroc, Purity ≥98%

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Synonym: Cenicriviroc; 497223-25-3; TBR-652; TAK-652; TBR652; TBR 652; 15C116UA4Y; CCR inhibitor

  • MDL: MFCD28502076
  • CAS Number: 497223-25-3
  • Compound CID: 11285792
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Cenicriviroc, soluble in DMSO and ethanol and insoluble in water, specifically binds to chemokine receptors. This binding blocks the receptors and prevents the corresponding chemokines from exerting their effects on immune cells, leading to reduced chemotaxis and cell activation.
Molecular Weight
696.94
Molecular Formula
C41H52N4O4S
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 94 mg/mL (134.87 mM); Water: Insoluble; Ethanol: 94 mg/mL (134.87 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Cenicriviroc can be leveraged to explore its dual antagonist activity on CCR2 and CCR5 in models of nonalcoholic steatohepatitis (NASH) and fibrosis.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
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