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CCR inhibitor TAK-220, Purity ≥98%

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Cat. No.: X24-07-ZQ147

CCR inhibitor TAK-220, Purity ≥98%

Synonym: 333994-00-6; CCR inhibitor; TAK220; TAK 220

CAS Number: 333994-00-6
Compound CID: 5275766

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

TAK-220 specifically binds to chemokine receptors. This binding blocks the receptors and prevents the corresponding chemokines from exerting their effects on immune cells, leading to reduced chemotaxis and cell activation. It targets HIV-1 (CTV), HIV-1 (CTV), HIV-1 (HHA), HIV-1 (HHA), HIV-1 (HKW), HIV-1 (HKW), HIV-1 (HNK), HIV-1 (HNK), HIV-1 (HTN), HIV-1 (HTN), HIV-1 (KK).

Molecular Weight

553.14

Molecular Formula

C₃₁H₄₁ClN₄O₃

Targets

HIV-1 (CTV): 0.72 nM (EC₅₀, in PBMCs); HIV-1 (CTV): 5 nM (EC₉₀, in PBMCs); HIV-1 (HHA): 0.55 nM (EC₅₀, in PBMCs); HIV-1 (HHA): 4 nM (EC₉₀, in PBMCs); HIV-1 (HKW): 1.7 nM (EC₅₀, in PBMCs); HIV-1 (HKW): 12 nM (EC₉₀, in PBMCs); HIV-1 (HNK): 1.7 nM (EC₅₀, in PBMCs); HIV-1 (HNK): 28 nM (EC₉₀, in PBMCs); HIV-1 (HTN): 0.93 nM (EC₅₀, in PBMCs); HIV-1 (HTN): 15 nM (EC₉₀, in PBMCs); HIV-1 (KK): 1.2 nM (EC₅₀, in PBMCs)

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

TAK-220 is a CCR inhibitor studied for its effects on pathways involved in immune response and potential therapeutic applications.

Publications

Publications (0)

Publications

Publications

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