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CDK inhibitor AT7519 HCl, Purity ≥98%

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Cat. No.: X24-05-ZQ736

CDK inhibitor AT7519 HCl, Purity ≥98%

Synonym: 902135-91-5; AT 7519; AT-7519; CDK inhibitor

CAS Number: 902135-91-5
Compound CID: 25033099

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

AT7519 HCl, soluble in warmed DMSO, warmed water and warmed ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK5/p35, AuroraA, and c-Abl.

Molecular Weight

418.7

Molecular Formula

C₁₆H₁₇Cl₂N₅O₂.HCl

Targets

CDK2/CyclinA: 47 nM; CDK5/p35: 13 nM; AuroraA: >10 μM; c-Abl: >10 μM

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 49 mg/mL (117.03 mM); Warmed water: 40 mg/mL (95.53 mM); Warmed ethanol: 26 mg/mL (62.09 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AT7519 HCl is used to study its inhibitory activity against multiple CDKs and its effects in cancer therapy.

Publications

Publications (0)

Publications

Publications

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