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CDK inhibitor AT7519, Purity ≥98%
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Cat. No.: X24-05-ZQ722

CDK inhibitor AT7519, Purity ≥98%

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Synonym: 844442-38-2; AT-7519; CDK inhibitor

  • CAS Number: 844442-38-2
  • Compound CID: 11338033
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Product Size
5 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AT7519, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK5/p35, AuroraA, and c-Abl.
Molecular Weight
382.2
Molecular Formula
C16H17Cl2N5O2
Targets
CDK2/CyclinA: 47 nM; CDK5/p35: 13 nM; AuroraA: >10 μM; c-Abl: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 9 mg/mL (23.54 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AT7519 can be used to study its role as a cyclin-dependent kinase (CDK) inhibitor and its effects on inducing apoptosis in cancer cells.
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