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Cat. No.: X24-05-ZQ706
CDK inhibitor BML-277, Purity ≥98%
Synonym: 516480-79-8; BML277; BML 277; CDK inhibitor
- CAS Number: 516480-79-8
- Compound CID: 9969021
Properties
Description
BML-277, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Chk2.
Molecular Weight
363.8
Molecular Formula
C20H14ClN3O2
Targets
Chk2: 15 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 65 mg/mL (178.67 mM); Water: Insoluble; Ethanol: 19 mg/mL (52.22 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BML-277 can be employed to study its selective inhibition of CHK1 and its effects on cell cycle regulation and DNA damage repair.
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