Cat. No.: X24-05-ZQ717
CDK inhibitor Centrinone-B, Purity ≥98%
Synonym: 1798871-31-4; LCR-323; LCR323; LCR 323; CDK inhibitor
- CAS Number: 1798871-31-4
- Compound CID: 118704753
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
Centrinone-B is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, PLK4, and PLK4 (G95L).
Molecular Formula
C27H27F2N7O5S2
Targets
Aurora A: 1239 nM (Ki); Aurora B: 5597.14 nM (Ki); PLK4: 0.59 nM (Ki); PLK4 (G95L): 497.53 nM (Ki)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Centrinone-B is used to investigate its selective inhibition of Centrinone and its effects on centrosome duplication in cell cycle regulation.
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