Properties
Description
CGP60474 is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1-Cyclin B, cdk2/cyclin A, CDK2/cyclinE, and CDK4/cyclin D.
Molecular Formula
C18H18ClN5O
Targets
CDK1-Cyclin B: 26 nM; cdk2/cyclin A: 4 nM; CDK2/cyclinE: 3 nM; CDK4/cyclin D: 216 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
CGP60474 can be utilized to explore its broad inhibition of CDKs and its potential implications in cancer treatment.
