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CDK inhibitor NMS-1286937, Purity ≥98%
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Cat. No.: X24-05-ZQ703

CDK inhibitor NMS-1286937, Purity ≥98%

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Synonym: 1034616-18-6; NMS1286937; NMS-P937; CDK inhibitor

  • CAS Number: 1034616-18-6
  • Compound CID: 49792852
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NMS-1286937, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1, PLK2, and PLK3.
Molecular Weight
532.52
Molecular Formula
C24H27F3N8O3
Targets
PLK1: 2 nM; PLK2: >10 μM; PLK3: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 38 mg/mL (71.36 mM); Water: Insoluble; Warmed ethanol: 9 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
NMS-1286937 is used to explore its inhibitory activity against CHK1 and its potential in enhancing the efficacy of DNA-damaging agents in cancer treatment.
Publications
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