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CDK inhibitor ON123300, Purity ≥98%
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Cat. No.: X24-05-ZQ744

CDK inhibitor ON123300, Purity ≥98%

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Synonym: 1357470-29-1; ON123300; ON 123300; CDK inhibitor

  • CAS Number: 1357470-29-1
  • Compound CID: 56649281
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ON123300, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets ARK5, Cdk4/cyclin D1, CDK6/cyclinD1, and FGFR1.
Molecular Weight
429.23
Molecular Formula
C24H27N7O
Targets
ARK5: 5 nM; Cdk4/cyclin D1: 3.9 nM; CDK6/cyclinD1: 9.82 nM; FGFR1: 26 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 26 mg/mL (60.53 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ON123300 can be used to study the dual inhibition of CDK4/6 and ARK5 in cancer cells.
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