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Cat. No.: X24-05-ZQ699
CDK inhibitor Poloxin, Purity ≥98%
Synonym: 321688-88-4; Poloxin; CHEMBL3944542; [(Z)-(2-methyl-4-oxo-5-propan-2-ylcyclohexa-2,5-dien-1-ylidene)amino] 2-methylbenzoate; CDK inhibitor
- CAS Number: 321688-88-4
- Compound CID: 9613592
Properties
Description
Poloxin is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1 PBD, PLK2 PBD, and PLK3 PBD.
Molecular Weight
297.35
Molecular Formula
C18H19NO3
Targets
PLK1 PBD: 4.8 μM; PLK2 PBD: 18.7 μM; PLK3 PBD: 53.9 μM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Poloxin can be used to investigate the inhibition of Polo-like kinase 1 (Plk1) and its effects on mitotic progression and cancer therapy.
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