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CDK inhibitor R547, Purity ≥98%
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Cat. No.: X24-05-ZQ734

CDK inhibitor R547, Purity ≥98%

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Synonym: 741713-40-6; R-547; CDK inhibitor

  • CAS Number: 741713-40-6
  • Compound CID: 6918852
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Product Size
5 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
R547, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/CyclinB, CDK2/CyclinE, AuroraA, and CDK4/CyclinD1.
Molecular Weight
441.45
Molecular Formula
C18H21F2N5O4S
Targets
CDK1/CyclinB: 2 nM (Ki); CDK2/CyclinE: 3 nM (Ki); AuroraA: >5 μM (Ki); CDK4/CyclinD1: 1 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 56 mg/mL (126.85 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
R547 can be employed to study its inhibition of CDKs and its anticancer effects in preclinical models.
Publications
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