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CDK inhibitor SBE 13 HCl, Purity ≥98%
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Cat. No.: X24-05-ZQ709

CDK inhibitor SBE 13 HCl, Purity ≥98%

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Synonym: 1052532-15-6; SBE-13; SBE 13; CDK inhibitor

  • CAS Number: 1052532-15-6
  • Compound CID: 11948807
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SBE 13 HCl, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1, PLK2, and PLK3.
Molecular Weight
479.4
Molecular Formula
C24H27ClN2O4.HCl
Targets
PLK1: 200 pM; PLK2: >66 μM; PLK3: 875 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (187.73 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SBE 13 HCl is employed to study its effects as a selective CHK1 inhibitor and its role in sensitizing cancer cells to DNA-damaging agents.
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