Lentinan-cholesterol hemisuccinate, called CHEMS-lentinan, represents a modern bioconjugate merging the immunomodulatory β-1,3-1,6-glucan lentinan with CHEMS. This composite design leverages lentinan's three-strand helical geometry and tumor-inhibitory capabilities through thymic-mediated immune response activation.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
CHEMS
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-cholesterol hemisuccinate can be used for its potential to evaluate cholesterol-hemisuccinate conjugates for lipid raft incorporation in membrane fluidity studies.
Publications
Publications (0)
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Publications
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