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Cholesterol-PEG-modified vinorelbine tartrate liposomes
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Cat. No.: X26-05-ZQ2803

Cholesterol-PEG-modified vinorelbine tartrate liposomes

Synonym: Cholesterol-PEG vinorelbine tartrate LPs; Chol-PEG modified vinorelbine tartrate liposomes; PEG-cholesterol vinorelbine tartrate liposomes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This advanced engineered formulation features sterol-pegylated vinorelbine tartrate loaded liposomes. The structural matrix encapsulates the water-soluble salt compound vinorelbine tartrate entirely within its central aqueous core via an active remote-loading ammonium sulfate or acetate gradient matrix, while its exterior boundary is stabilized by a dense surface modification of cholesterol-polyethylene glycol (cholesterol-PEG) polymer conjugates. This precise configuration coordinates an active remote-loading vinca alkaloid matrix with a dense protective hydrophilic steric brush layer, altering overall membrane bending elasticity and surface hydration parameters to completely prevent physical vesicle aggregation and restrict passive drug leakage.
Source
Custom synthesis
Functional Group
Cholesterol-Vinorelbine tartrate
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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