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Combretastatin A4 phosphate-modified liposomes (CA4P-LPs)

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Cat. No.: X26-05-ZQ2237

Combretastatin A4 phosphate-modified liposomes (CA4P-LPs)

Name: Combretastatin A4 phosphate-modified liposomes (CA4P-LPs)
SKU: X26-05-ZQ2237

Inquiry

Synonym: Combretastatin A4 phosphate LPs; CA4P-modified liposomes; CA4P-LPs liposomes; CA4P-LPs

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This formulation features combretastatin A4 phosphate liposomes (Combretastatin A4 phosphate-modified liposomes (CA4P-LPs)) engineered to encapsulate a water-soluble vascular disrupting agent within a stable vesicle matrix. The structural matrix encapsulates the hydrophilic prodrug combretastatin A4 phosphate (CA4P) entirely within the central aqueous reservoir of a rigid phospholipid-cholesterol bilayer shell. This precise configuration locks the prodrug within the core, protecting its phosphate ester linkage from premature chemical hydrolysis or phosphatase degradation in open laboratory test setups, while minimizing passive membrane diffusion.

Source

Custom synthesis

Functional Group

Combretastatin A4 phosphate

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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