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CREKA peptide-modified docetaxel-loaded liposomes (CREKA-lipo-DTX)

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Cat. No.: X26-05-ZQ1658

CREKA peptide-modified docetaxel-loaded liposomes (CREKA-lipo-DTX)

Name: CREKA peptide-modified docetaxel-loaded liposomes (CREKA-lipo-DTX)
SKU: X26-05-ZQ1658

Inquiry

Synonym: CREKA peptide docetaxel liposomes; CREKA-modified DTX-loaded LPs; CREKA-lipo-DTX

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This formulation features CREKA pentapeptide-modified docetaxel-loaded liposomes (CREKA-lipo-DTX) engineered with a sterically stabilized affinity surface. The vesicular structure incorporates the hydrophobic taxane docetaxel (DTX) directly into the hydrocarbon tail region of a stable phospholipid bilayer, while the exterior surface is functionalized with specific cysteine-arginine-glutamic acid-lysine-alanine (CREKA) tumor stroma-targeting pentapeptides linked via polymer-lipid anchors. This surface modification alters the overall surface topography, membrane packing density, and surface charge profile. The resulting vesicles exhibit high colloidal stability and provide a defined model for peptide surface interaction assays in cell-free environments.

Source

Custom synthesis

Functional Group

CREKA peptide; Docetaxel

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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