Lentinan-cRGD peptide, referenced as cRGD-lentinan, engineers a cyclic RGD-conjugated derivative for enhanced integrin recognition. The structurally optimized hybrid preserves lentinan's triple-helix configuration while directing immune-mediated tumor suppression via thymic activation pathways.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
cRGD
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-cRGD peptide can be used for its potential to improve tumor homing through cyclic RGD peptide modifications in metastatic cancer models.
Publications
Publications (0)
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Publications
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