Properties
Description
Lentinan-cRGD peptide, referenced as cRGD-lentinan, engineers a cyclic RGD-conjugated derivative for enhanced integrin recognition. The structurally optimized hybrid preserves lentinan's triple-helix configuration while directing immune-mediated tumor suppression via thymic activation pathways.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-cRGD peptide can be used for its potential to improve tumor homing through cyclic RGD peptide modifications in metastatic cancer models.