Properties
Description
Through covalent conjugation, the cRGD-xylan complex merges peptide-mediated cellular targeting with xylan's β-1,4-linked xylose scaffold sourced from renewable hemicellulose. This biomaterial configuration enhances colloidal stability through the carbohydrate's inherent water affinity.
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-cRGD peptide can be used for its potential to optimize tumor-targeted delivery via cyclic integrin-binding peptide conjugation in metastasis models.
