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c(RGD)fk-mediated doxorubicin-dihydroartemisinin nanoparticle liposomes
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Cat. No.: X26-05-ZQ2896

c(RGD)fk-mediated doxorubicin-dihydroartemisinin nanoparticle liposomes

Synonym: c(RGD)fk doxorubicin-dihydroartemisinin NP LPs; c(RGD)fk-mediated DOX-DHA nanoparticle liposomes; c(RGD)fk DOX-dihydroartemisinin nanoliposomes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly advanced multi-functional targeted formulation features c(RGD)fk peptide functionalized liposomes co-loaded with doxorubicin and dihydroartemisinin nanoparticles. The complex structural framework encapsulates pre-formulated dihydroartemisinin core nanoparticles alongside the hydrophilic anthracycline doxorubicin within its aqueous core matrices, while its exterior lipid bilayer shell is surface-modified with specific cyclic arginylglycylaspartic acid-d-phenylalanyl-lysine (c(RGD)fk) targeting peptides linked via covalent polymer-lipid anchors. This precise modification coordinates a dense target-mimetic ligand array with a dual-phase multi-cargo core, altering overall membrane bending elasticity to completely prevent physical particle aggregation and suppress cargo crystallization across variable laboratory media backgrounds.
Source
Custom synthesis
Functional Group
c(RGD)fk cyclic peptide; Doxorubicin; Dihydroartemisinin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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