Fluorescent labeling via xylan-Cy5 conjugation demonstrates how cyanine dye optical properties can be synergized with xylan's carbohydrate matrix, utilizing hydroxyl group reactivity for covalent attachment without compromising photostability.
Glycan Name
Xylan
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Cy5
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-Cyanine5 can be used for its potential to track lymphatic drainage patterns through cyanine dye labeling in rodent models.
Publications
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Publications
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