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Calpeptin, soluble in DMSO and ethanol and insoluble in water, obstructs cysteine proteases, enzymes implicated in numerous diseases due to their role in protein degradation. It targets Calpain I (human platelets), Calpain I (porcine erythrocytes), Calpain II (porcine kidney), and papainb.
Molecular Weight
362.47
Molecular Formula
C20H30N2O4
Targets
Calpain I (human platelets): 40 nM (ID50); Calpain I (porcine erythrocytes): 52 nM (ID50); Calpain II (porcine kidney): 34 nM (ID50); Papainb: 138 nM (ID50)
Calpeptin is utilized to inhibit calpain, aiding the investigation into cellular processes like signal transduction, proliferation, and apoptosis.
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