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Cytochrome P450 inhibitor, Ketoconazole, Purity ≥98%
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Cat. No.: X24-08-YM376

Cytochrome P450 inhibitor, Ketoconazole, Purity ≥98%

Synonym: 65277-42-1; Nizoral; Extina; Xolegel; Kuric; 1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone

  • MDL: MFCD00058579
  • CAS Number: 65277-42-1
  • Compound CID: 456201
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Product Size
100 mg; 200 mg; 500 mg; 1000 mg
Price
Datasheet
MSDS
Properties
Description
Ketoconazole, soluble in warmed DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450. It targets the cyclosporine oxidase and testosterone 6 beta-hydroxylase.
Molecular Weight
531.4
Molecular Formula
C26H28Cl2N4O4
Targets
Cyclosporine oxidase: 0.19 mM; Testosterone 6 beta-hydroxylase: 0.22 mM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 5 mg/mL (9.4 mM); Water: insoluble; Ethanol: 7 mg/mL; In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL
Applications
Ketoconazole is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of fungal infections such as athlete’s foot, ringworm, and candidiasis.
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