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Cytochrome P450 inhibitor, TH-302, Purity ≥98%

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Cat. No.: X24-08-YM386

Cytochrome P450 inhibitor, TH-302, Purity ≥98%

Synonym: 918633-87-1; TH302; Evofosfamide; 2-Bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine

CAS Number: 918633-87-1
Compound CID: 11984561

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

TH-302, soluble in DMSO, warmed water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.

Molecular Weight

Molecular Formula

C₉H₁₆Br₂N₅O₄P

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 80 mg/mL (178.15 mM); Water (warmed): 9 mg/mL (20.03 mM); Ethanol: 80 mg/mL (178.15 mM); In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL

Applications

TH-302 is a metabolism inhibitor that can be used for its ability to release cytotoxic agents in low-oxygen environments typical of solid tumors.

Publications

Publications (0)

Publications

Publications

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