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Cytochrome P450 inhibitor, TOK-001, Purity ≥98%
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Cat. No.: X24-08-YM385

Cytochrome P450 inhibitor, TOK-001, Purity ≥98%

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Synonym: 851983-85-2; VN/124-1; Galeterone; (3S,8R,9S,10R,13S,14S)-17-(Benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol

  • MDL: MFCD16660907
  • CAS Number: 851983-85-2
  • Compound CID: 11188409
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TOK-001, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450. It targets the androgen receptor and CYP17.
Molecular Weight
388.3
Molecular Formula
C26H32N2O
Targets
Androgen Receptor: 384 nM; CYP17: 300 nM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 21 mg/mL (54.04 mM); Water: insoluble; Ethanol (warmed): 36 mg/mL (92.65 mM); In vivo: 0.5% hydroxyethyl cellulose, 28 mg/mL
Applications
TOK-001 is a metabolism inhibitor that plays a key role in blocking the effects of androgens, which are hormones that drive prostate cancer cell growth.
Publications
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