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D-Mannose-modified lung-targeted irinotecan hydrochloride cationic liposomes

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Cat. No.: X26-05-ZQ2824

D-Mannose-modified lung-targeted irinotecan hydrochloride cationic liposomes

Name: D-Mannose-modified lung-targeted irinotecan hydrochloride cationic liposomes
SKU: X26-05-ZQ2824

Inquiry

Synonym: D-Mannose-modified lung-targeted irinotecan HCl cationic LPs; D-Mannose lung-targeted irinotecan HCl cationic liposomes; D-Mannose functionalized lung-targeted irinotecan HCl cationic liposomes

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced complex formulation features mannose functionalized and irinotecan hydrochloride loaded cationic liposomes. The structural framework encapsulates the hydrophilic camptothecin derivative irinotecan hydrochloride within its central aqueous core, utilizing a lipid bilayer matrix formulated with cationic lipids to establish a robust positive surface potential, whose exterior boundary is surface-modified with specific D-mannose carbohydrate residues linked via lipid anchors. This complex configuration coordinates a dense target-mimetic carbohydrate interface and high electrostatic stability with an optimized camptothecin matrix, completely preventing physical vesicle aggregation while shielding the volatile lactone ring core from rapid chemical hydrolysis in open laboratory testing media.

Source

Custom synthesis

Functional Group

D-Mannose; Irinotecan hydrochloride; Cationic lipid

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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