Lentinan-diphenylcyclooctyne, called DBCO-lentinan, represents a modern bioconjugate coupling the immunotherapeutic β-1,3-1,6-glucan lentinan with DBCO. This composite entity applies lentinan's three-dimensional helical configuration and tumor-suppressing properties through thymic-mediated immune activation pathways.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
DBCO
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-diphenylcyclooctyne can be used for its potential to apply diphenylcyclooctyne tags for strain-promoted click chemistry in zebrafish embryo labeling.
Publications
Publications (0)
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Publications
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